OF THE ALIMENTARY TRACT 91 



In active phases of the disease when the patient 

 is in bed or may be so confined, chiniofon (yatren) 

 may be an effective drug, given in cachets of 3 grams 

 per day for 10 consecutive days, accompanied by a 

 liquid diet. It may also be used by rectum. It may 

 produce diarrhoea itself. 



In the experience of Jones and Turner (1929) 

 yatren is a valuable drug in intestinal amoebiasis, 

 particularly in dysentery, given in pills of 0.25 gms. 

 each, coated, with phenyl saUcylate, 1 gram by mouth 

 three times daily during the first and third week, 

 none in the second. No restriction of diet or con- 

 finement to bed is necessary. Children may be given 

 a proportionate dose. There were no toxic manifes- 

 tations but the drug may cause diarrhoea. The 

 eft'ect is claimed to be directly upon the amoeba in 

 the intestine, and ulcers of the rectum healed in from 

 seven to fourteen days. 



Decks (1928) reaffirms the excellence of his treat- 

 ment with bismuth and emetine in amoebic dysen- 

 tery, and says that the newer measures of treatment 

 by bismuth-emetine-iodide, yatren, and stovarsol 

 have not given equally good results. 



Another valuable drug of comparatively recent 

 introduction in the therapeutic armamentarium 

 against amoebiasis is acetarsone (stovarsol), an ar- 

 senical preparation. Several arsenical drugs appear 

 to be amoebicidal in much higher dilution than other 

 so-called specifics for amoebiasis. According to Kof- 

 oid and Wagener (1925) the lethal dilution of stovar- 



