204 PROTOZOAN PARASITISM 



antidiosis; there are the two states, chronic balan- 

 tidiosis and acute balantidial dysentery. 



BALANTIDIAL DYSENTERY 



The acute phase of the disease is the unusual con- 

 sequence of infection, the acute attack, or the end 

 result. 



In this condition the organism is known to be a 

 tissue invader. Manlove (1917) records that bal- 

 antidiosis is a relatively unimportant cause of death 

 in the Philippines, but may cause considerable mor- 

 bidity, being characterized by colitis varying from 

 simple catarrh to deep ulceration. Strong (1904) 

 reviewed 127 cases in the literature of that time, 

 wdth 35 deaths and 32 autopsies, including one of his 

 own, of which 28 showed ulcerative colitis and 3 

 chronic catarrhal colitis. Walker (1913) produced 

 experimental infection of monkeys with the organ- 

 ism from man and pigs and studied the evolution of 

 the experimental disease. 



He found that Balantidiuvi coll does not enter 

 through the lesions of colitis of other causes but 

 through the sound intestinal epithelium, becoming 

 the primary etiologic factor in balantidial dysentery. 

 The early lesions consisted of hyperemia with or 

 without punctiform hemorrhages, showing histo- 

 logically, vascular dilation, minute hemorrhages, 

 round-cell infiltration and eosinophilia. Some of the 

 later submucosal abscesses were bacteriologically 



