26 



MACROMOLECULAR COMPLEXES 



o.r 



r 





SiiUiiJiiB 



7j2^ri''»t 



Fig. 7. Reconstituted native-type fibril, showing the characteristically polar- 

 ized intraperiod band pattern. The axial period of ca. 700 A is indicated by 

 the row of dots, and the longitudinally staggered packing of the protofibrils 

 by the arrangement of arrows along the lower edge of the figure, (a) Stained 

 with PTA. XI 30,000. (From Hodge, 1959b.) (b) Indicates the currently ac- 

 cepted band nomenclature. X230,000. 



bands observable along the length of the TC, but that many of these 

 bands differ markedly in relative intensities in the two fingerprints. 

 Hence, we appear to have direct evidence that polar groups, both 

 basic and acidic, are localized in narrowlv defined regions at distinct 

 and characteristic loci along the length of the TC macromolecules. 

 The narrowest bands observed are in the range 15-20 A wide. The 

 intensity differences observed also indicate that while basic groups 



