INTERACTION OF COLLAGEN MAC ROMOLEC U LES 



29 



^f ?!- ^3 ^ 



3 



C.C 



o. 



r 



Fig. 10. Higher magnification view of a region in the same preparation as 

 shown in Fig. 9, to illustrate the precise correspondence of the bands in the 

 SLS-type structure with those in the native-type structure. As indicated in the 

 band nomenclature (proposed by Hodge and Schmitt, 1960), each band in 

 the native-type structure exhibits continuity with four "equivalent bands" of 

 differing intensity in the SLS-type structure, and its intensity is therefore a func- 

 tion of the intensities of all four of the corresponding SLS bands. Thus, for 

 example, /^ = (/c/4) {\h + \h + /a.) + U^, where /<; is the intensity of the 6 band 

 in the native-type structure, /«!, U-i, \h, and U^ are the intensities of the corre- 

 sponding "equivalent bands" in the SLS-type structure, and /c is a constant, the 

 value of which will depend on the degree of additivity of the band intensities. 

 The close correspondence in the relative band intensities obtained by direct 

 optical synthesis with those in the native-type fibril (Fig. 8) indicates that the 

 actual value of /c must be close to unity, as would be expected if the staining 

 intensity is proportional only to the concentration of polar side-chain groups. 

 X 21 5,000. (From Hodge and Schmitt, 1960.) 



