660 



Subject Index 



Haema tin-carbon monoxide compounds 



328 

 Haematin compounds, spectra of 325 

 Haematin propionate groups, decrease in 



acid strength of, 176 

 Haematoporphyrin, redox potential 54 



spectra of 150,151 

 Haem-binding, and Bohr effect 94-96 

 Haem-globin linkage 173-193 

 Haemin, combination with proteins 95 

 contribution to spectra of haemochromo- 



proteins 149-155, 157 

 conversions from porphyrins 323 

 in cytochrome oxidase 335 

 removal of iron from 322 

 Haemin a, in cytochrome oxidase 335 

 isolation of 320-321 

 measurement of 324-325 

 molecular weight 284 

 purification of 320-322 

 Haemin chloride, structure of 61 

 Haemin chromoproteins, absorption spectra 

 of 142-168 

 absorption spectra, a and (i bands 149, 

 153, 157-159, 167, 171 

 analysis and notation of bands 149 

 contribution of haemin 149-155, 157 

 contribution of porphyrin 1 62- 1 65 

 contribution of proteins 156-157, 167 

 graphic analysis 146-149 

 graphic-mathemetical analysis 167- 

 168 

 correlation of spectroscopic pattern with 



electronic structure 158 

 spectra of, location of maxima 153 

 notation 146 

 Haemin dicyanide, spectra of 145, 150, 



151 

 Haemochromes, combination with carbon 

 monoxide 98 

 effect of ligands in 5th and 6th co-ordina- 

 ting positions 65-67 

 spectra of 72-73, 142 

 structure of 72-73 

 Haemochromes a, formation of 330 

 Haemoglobin, absorption bands in yeast 

 233-235 

 activity as oxidases 84-87 

 addition of sodium laurate 85 

 addition of sodium salicylate 85 

 affinity for ethyl isocyanide 84 

 amino acid content 90 

 binding in 50 



binding reactions with ethylcyanide 81 

 binding reactions with ethyl isocyanide 



80-84 

 binding sites of 95, 100 



Haemoglobin — cont. 



binding with oxygen molecule 103 



Bohr effect 187 



combination with carbon monoxide 

 98 



denaturation of 94-96 



denaturation of globin from 190 



dissociation curves 174 



haem binding affinity of 91 



haem-haem reaction of 86. 173, 187 



haem-protein linkage in 179-180 



imadazole hypothesis 48-49 



linkage of iron and protein in 190 



magnetic moment 1 1 1 



modification of protein moieties 84-87 



oxygen dissociation curves 186 



oxygenation of 102-104 



reaction with cyanide ion 101 



relationship between molecular structure 

 and physiological activity 173-193 



spectra of 42, 105, 119, 142 



steric hindrance 173 

 Haemoglobin derivatives, spectra of 162- 



164 

 Haemoprotein(s), absorption spectra of. 

 bands in region of 830 and 280 m/« 

 171-172 



absorption spectra of, interpretations 

 170-172 



Bohr effect in 80-84 



co-ordination in 109-110 



effect of ionic strength on autoxidation 

 573-574 



energy transfer in 600 



haem-binding groups in 94-96 



haem-haem interaction in 80-84 



in purple photosynthetic bacteria 419- 

 431 



chemical properties 421-423 

 classification of 430-431 

 comparison v^th cytochrome o 434 

 enzyme properties 428-429 

 extinction coefficients 427 

 general properties 419-430 

 immunochemical properties 423 

 metal content 427-428 

 oxidase function of 435 

 physical properties of 420-421 

 reduction by cytochrome c 428^29 

 spectroscopic properties 423-427 



interaction of 9 



kinetic data of reactions 16,17 



linked ionizations 96-97 



models for 76 



modification of secondary structure of 

 molecules 80-94 



oxidation states 252-254 



