Waksman 



— 178 — 



Actinomycetes 



mycosis such as those caused by N. asteroides and N. madnrae do not 

 produce clubs; even A. hovis may not form clubs in some tissues, under 

 certain conditions. 



Emmons (106) defined actinomycosis as "an infection caused by 

 invasion of the host by some species of Actinomyces." Several forms 

 were recognized, namely, actinomycosis of the skin, actinomvcotic 



Fig. 37.- An earh' study of the structure of an actinomvces colon\' from a 

 bronchopneumonic nodule Qroni Butterfield, 58). 



meningitis, lung infection, Madura foot, actinomycotic types of myce- 

 tomas. The presence of sulfur granules is frequently considered as a 

 diagnostic symptom of actinomvcosis. Granules mav be produced, how- 

 ever, by other organisms, and some actinomvcetes do not form granules 

 on clubs (496). Club formation is frequently considered (24, 276, 

 519) as evidence of diminished growth of the host, the presence of 



