SPECIES OF STREPTOMYCES 59 



37. Streptomyces achromogenes Okami and Umezawa. (Okami, Y., 

 and Umezawa, H., Japan. Med. J., 6, 1953.) 



Aerial mycelium: Fine branching aerial hyphae, no spirals. Spores cylin- 

 drical. 



Synthetic glycerol agar: Colorless to brownish, restricted growth; scant 

 white to dark grayish-colored aerial mycelium; brown soluble pigment. 



Glucose-asparagine agar: Growth yellowish brown, restricted; aerial 

 mycelium scant, yellowish white; reverse of growth brown; soluble pig- 

 ment none or slightly brown. 



Nutrient agar: Growth wrinkled, elevated, colorless to brownish; no aerial 

 mycelium; no soluble pigment. 



Potato: Growth yellowish brown to brownish, fine, wrinkled; aerial my- 

 celium white, powdery; no soluble pigment at first, later reddish brown. 



Gelatin: Growth yellowish brown, restricted; no aerial mycelium; slightly 

 brown soluble pigment; liquefaction very weak. 



Milk: Surface growth poor; no aerial mycelium; no soluble pigment; coag- 

 ulation and slow peptonization. 



Egg media: Growth reddish brown, wrinkled; no aerial mycelium; no 

 soluble pigment. 



Loeffler's serum media: Growth elevated, wrinkled, colorless to brownish; 

 no aerial mycelium; no soluble pigment; no liquefaction. 



Blood agar: Growth brownish, wrinkled, poor; no aerial mycelium; no 

 soluble pigment; no hemolysis. 



Nitrate : Reduction to nitrite. 



Antagonistic properties: Produces an antiviral agent, achromoviromycin. 



Remarks: This culture resembles Streptomyces diastaticus and Strepto- 

 myces fimicarius. This strain differs from the former in the points of spiral 

 formation, hemolysis, liquefaction of gelatin and proteolytic action of milk; 

 it differs from the latter in the points of liquefaction of coagulated serum. 

 This species is characterized by the brown pigmentation on synthetic agar 

 only. 



38. Streptomyces noursei Hazen. (Unpublished. Preliminary data by 

 Hazen, E. L., and Brown, R., Proc. Soc. Exp. Biol. Med., 76, 1951, 93.) 



Vegetative growth: Good gray to brown growth, much folded on various 

 organic and certain synthetic media; diffusible pink to purple pigment fre- 

 quently produced. 



Aerial mycelium: Well developed white to shell-pink; straight, curved 

 and spiral-forming sporulating hyphae. Spores round to oval. 



Synthetic agar: Scanty, colorless, flat growth, no aerial mycelium. 



Glucose agar: Good, folded growth. White aerial mycelium, turning gray. 

 Reverse of growth brown, medium often becoming darkened throughout. 



