SPECIES OF STREPTOMYCES 73 



and Pridhara, T. G., J. Bacterid., 56, 1948, 467-477; Pridham, T. G., and 

 Gottlieb, D., J. Bacterid., 56, 1948, 107-114.) 



Vegetative growth: Hyphae colorless, monopodial branches, 0.9-1.8 p in 

 diameter. 



Aerial mycelium: Straight or slightly and irregularly curved, 1.0-1.8 p 

 in diameter, lavender under microscope, gray to light tan or pink without 

 magnification. Spores oval to oblong, 0.4-0.8 by 0.7-1.6 p. 



Synthetic agar: Growth light lavender-colored. 



Glucose agar: Soluble pigment dark. 



Potato: Growth abundant, gray. 



Gelatin: Liquefaction rapid; soluble pigment dark. 



Milk: Peptonization; soluble pigment dark. 



Starch : Growth white to lavender. 



Nitrate: Reduction positive. 



Dorset's egg medium : Growth white to gray. 



Loeffler's serum: Growth dark brown. 



Tyrosine agar : Reaction positive. 



Antagonistic properties: Produces chloramphenicol, a neutral compound 

 active against various gram-positive and gram-negative bacteria, rickett- 

 siae, and larger viruses. 



Remarks: Good growth with xylose, arabinose, rhamnose, d-glucose, d- 

 mannose, d-fructose, d-galactose, cellobiose, starch, dextrin, glycerol, ace- 

 tate, citrate, succinate, and salicin. Slight or no growth with d-ribose, su- 

 crose, raffinose, inulin, erythritol, dulcitol, mannitol, sorbitol, inositol, and 

 malate. No growth with formate, oxalate, tartrate, salicylate, phenol, 

 o-cresol, m-cresol, p-cresol. 



Syn. S. pheochromogenus var. chlorom.yceticus Okami. 



60. Streptomyces virginiae Grundy, Whitman, Rdzok, Rdzok, Hanes, 

 and Sylvester. (Grundy, W. E., Whitman, A. L., Rdzok, E. C., Rdzok, E. 

 J., Hanes, M. E., and Sylvester, J. C., Antibiotics & Chemotherapy, #, 

 1952, 399-408.) 



Vegetative growth: Cream-colored to light brown on complex media; 

 soluble pigment diffusible, light brown. On synthetic media growth white 

 to cream-colored, with pink or grayish lavender aerial mycelium. Undulat- 

 ing mycelium about 1 p in diameter with short thinner side branches. 



Aerial mycelium: Aerial hyphae long, grayish pink or lavender. Most 

 of the sporulating hyphae are straight, but occasionally a spiral is observed 

 at or near the tip of the hypha. These spirals vary from tightly closed knots 

 to loose open spirals. Spores cylindrical, 1.1-1.5 by 0.75-1.0 p. 



Synthetic glucose agar: Growth sparse, cream-colored; aerial mycelium 

 light grayish lavender. No soluble pigment. 



Nutrient agar: Growth sparse, white, turning cream-colored; aerial myce- 



