174 THE ANTIBIOTICS 



f. Other compounds related to the streptomycins. 

 Dextromycin 



2. Soluble in water and insoluble in organic solvents; some are known 

 to contain amino acids, amino sugars, and unidentified fragments. 

 Active also against fungi. 



a. Contain two amino acids and one amino sugar, delayed 

 toxicity Streptothricin 



(Streptothricin VI) 



b. Compounds similar to, but not identical with, streptothricin. 



Pleocidin 

 (Pkocidin A) 



c. Other compounds similar to streptothricin. 



Antibiotic 136 



d. Unidentified fragments, plus an amino acid, identical with 

 one of above. 



Streptolin A, B 



e. Chemically unidentified, biological activity similar to strepto- 

 thricin Actinorubin, 



Lavendulin, Antibiotic EI 5 



f. Same as above, but greater activity against cocci. 



Streptin 



g. Yellow compound, more active in acid than in alkaline media. 



Flaveolin 



3. Compounds related to above, not active against fungi, active against 

 bacteria resistant to streptomycin and streptothricin. 



a. Active against numerous bacteria and mycobacteria. 



Neomycin 



(Neomycin B, Streptothricin BII) 



b. Degradation products differ from those of neomycin B. 



Neomycin C 

 (Streptothricin BI) 



c. Biological or chemical degradation product of neomycin. 



Neamine 

 (Neomycin A) 



d. Substances related to the neomycins. 



Catenulin 



Flavomycin 



Framycetin 



e. Limited activity against Mycobacterium tuberculosis, low toxic- 

 ity Roseomycin 



