ANTIBIOTIC GROUPS 179 



b. Comparatively nontoxic to mice. 

 Carbomycin 

 Erythromycin 

 Leucomycin 

 V. Active mainly against Corynebacterium diphtheriae. 



Thermomycin 

 VI. Active mainly against Sarcina lutea. 



Sarcidin 

 VII. Substances not falling into the preceding groups. 

 1. Pigmented. 



a. Yellow-green pigment at neutral reaction. 



Actinomycelin 



b. Yellow substances, containing no N or S. 



Resistomycin 



c. Yellow substance containing N and maybe S. 



Phalamycin 



d. Violet pigment. 



Mycetin, Rhodocidin 



e. Red pigments not acting as pH indicators. 



a 1 . Does not yield amino acids by acid hydrolysis. 



Nocardianin 

 b 1 . Yield amino acids by acid hydrolysis. 

 a 2 . Does not contain allo-isoleucine. 



Actinomycin 

 b 2 . Related substance not fully described. 



Actinomycin Ji 

 c 2 . Contains allo-isoleucine. 

 Actinomycin C 



f. Red pigments acting as pH indicators. Red to yellow at 

 acid reaction. Blue to purple at alkaline pH. 



a 1 . Slightly soluble in alcohols. Light-absorption maxima at 

 560 and 523 mn 



Actinorhodin 

 b 1 . Soluble in alcohols. 



a 2 . Unstable at acid and alkaline reaction. Light-absorp- 

 tion maxima at 575, 542, 533 and 504 mn. 

 Rhodomycin 

 b 2 . Unstable at alkaline reaction. Insoluble in water. 

 Light-absorption maxima at 580, 540 and 235 mp. 

 Rhodomycetin 

 c 2 . Unstable at alkaline reaction, soluble in water. 

 SKCC 1377 



