NONSPORE-FORMING BACTERIA 



TABLE 13 {continued) 



97 



ANTAGONIST 



Streptococci 



Streptococci 



Staphylococci 



Micrococci 



Diplococci and 

 pneumococci 



K. -pneumoniae 



P. vulgaris 



P. avicida 

 Myxobacteria 



Anaerobic bac- 

 teria 



ORGANISMS AFFECTED 



B. anthracis, C. difhtheriae 



B. anthracis, Ph. tumefaciens, 

 S. lactis, P. festis, L. bul- 

 garicus 



Gram-positive bacteria, C. 

 difhtheriae, P. festis 



V. comma, M. tuberculosis, 

 E. tyfhosa, Br. melitensis 



Various bacteria 



B. anthracis, C. difhtheriae, 

 P. festis 



B. anthracis, P. festis, CI. 

 sforogenes 



B. anthracis, E. tyfhosa 



Plant-disease-producing 

 bacteria 



M. tuberculosis, B. anthracis 



KNOWN PROPERTY 



Activity not associ- 

 ated with hemoly- 

 sis or virulence 



Thermostable, non- 

 filterable substance 



Thermolabile sub- 

 stance 



Active filtrate 



Thermostable lytic 

 substance 



REFERENCES 



53, 110, 187, 233, 



303,670,711, 836 



70, 244, 802, 1007 



53, 155,215,244, 



247 



213, 214, 580, 625, 

 670 



213, 214, 243, 244, 

 370, 580,677, 766 



677>7"5 853 

 36, 244, 923, 985 



440, 708 



S. marcescensy Ps. fluorescenSj and Sacckaromyces cereviseae; spore 

 formation by the last was favored (800). 



The specific antagonistic action of Ps. aeruginosa upon various bac- 

 teria was found by early investigators to be due to the production of an 

 active heat-resistant substance. By filtering the culture through a Berk- 

 feld, evaporating to a small volume, dialyzing through a parchment 

 membrane, precipitating with alcohol, and drying over sulfuric acid, a 

 preparation was obtained which was designated as pyocyanase (see 

 p. 51). It had, even in very low concentrations, a marked destructive 

 effect upon diphtheria, cholera, typhus, and plague organisms, as well 

 as on pyogenic streptococci and staphylococci. It rapidly dissolved V. 



