GENERAL INDEX 



41: 



Para-amino-benzoic acid, effect on 

 penicillin, 226-227, 229, 239- 

 240, 256, 325 



Paracolon bacteria, 102 



Parasiticin, 329 



Parasitism, 13, 37-38 



Paratyphoid bacteria, 93 



Partial disinfection of soil, 312 



Partial sterilization of soil, 155, 



304 



Passive antagonism, 48 



Pathogenic organisms 

 in fecal wastes, 21—22 

 in soil, 14-15, 16-18, 26-35 



Patulin. See Clavacin 



Penatin, 70, 133, 169, 170, 173, 207, 



329 



Penicidln, 133, 140, 174, 213, 320, 



Penicillamine, 207 



Penicillic acid, 133, 140, 174, 182, 

 209, 228, 245, 319, 320, 329 

 chemical nature, 174, 177 

 structural formula, 182 

 Penicillin, 81, 131, 163, 169, 170, 

 174, 213, 298, 299, 319, 320, 



329 

 administration, 272 

 animal experiments, 272—275 

 antiluminescent activity, 81, 82 

 as prophylactic, 275 

 assay, 204-205 

 bactericidal action, 221, 234—235, 



249-250 

 bacteriostatic spectrum, 76, 220, 236 

 chemical nature, 174, 178, 200- 



207 

 chemotherapy, 274, 275—280 

 compared with 



chemical substances, 70, 221—222 



other antibiotics, 219, 222, 232, 

 237, 242 



sulfanilamide, 237 



sulfathiazole, 235 



sulfonamide, 237-240, 268, 269, 

 277 

 crystals, frontisfiece 

 differentiation of bacteria by, 259- 



260 

 discovery, 132, 314—316 



Penicillin (cont.) 



effect of other agents, 226 



effect of reaction, 234 



effect on bacteria, 80, 225, 234, 



236-237, 247-248, Fig. 27 (p. 



251), 252 

 effect on cell morphology, 251—253 

 effect on fungi, 236 

 effect on metabolism, 255 

 effect on phage, 165 

 effect on sea urchin eggs, 240 

 effect on virus, 165, 166 

 failures, 279 



inactivation, 239, 240, 255-256 

 inhibitor, 259 

 in wounds, 3 1 7 

 isolation, 202-204 

 lysis of bacteria by, 234 

 measurement, 73, 75—78, 80-85 

 medium, 65—67 

 mode of action, 234—240 

 pharmacology, 279 

 production, 132-140, 200-201, 



205 

 resistance of bacteria to, 235, 257— 



259, 270 

 selective action, 267—269 

 sporocidal action, 235, 252 

 submerged culture for production, 



137-139 

 surface culture for production, 137- 



138 

 therapeutic value, 266, 267—280, 



317 

 toxicity, 178, 267-269, 271, 272, 



276 

 Penicillin B. See Penatin 

 Penicillin F, 139, 206, 272, 275 

 Penicillin G, 139, 206, 273, 275 

 Penicillin K, 139, 206, 273, 275 

 Penicillin X, 139, 140, 2o6, 236, 273, 



275 

 Penicillinase, 82, 147, 226, 230, 255— 



256, 258 

 Penicillin-like substances, 140 

 Peptones as bacteriostatic agents, 183 

 Persisters, 270 

 Pfeiffer's bacillus, 259 

 Phage in soil, 6, 9 



