342 M. Morrison and E. Stotz 



wo-octane extraction of the preparation, the addition of succinate results in a 

 complete reduction of cytochrome q and only partial reduction of cyto- 

 chrome b. According to the foregoing scheme, the cytochrome Z?-inhibitor 

 compound cannot be reduced and consequently remains in the oxidized form 

 after having reduced the cytochrome q. 



Studies are now in progress which are designed to isolate and characterize 

 cytochrome-inhibitor compounds. It is hoped by such studies to clarify the 

 role of the electron carriers in oxidative phosphorylation. 



A cknowledgemen ts 



The research in this report was supported by Grant No. H-1322 from the 

 National Heart Institute, National Institute of Health. 



One of the authors (M.M.) was supported by a Senior Research Fellowship 

 SF-47 from the U.S. Public Health Service. 



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