science cannot give answer, why should he be expected to 1 QS 

 know? And as to the patient, well it's his disease, isn't it? 



And so after some weeks, and still very ill, the meat butcher 

 tired of his hospital residence and left. 



But Wherry had not forgotten his man. On December 

 fourth he again scraped a bit of tissue from an ulcerated patch, 

 stirred it up in salt water and injected it into a defenseless 

 guinea pig. Five days later it was dead. Autopsy showed its 

 lungs, spleen and liver to be riddled with minute patches of 

 dead tissue; but most careful staining methods, attempts at 

 culture, etc, revealed nothing certainly identifiable as bac- 

 teria. So Wherry took of the spleen of this animal and injected 

 it into a second. In five days it, too, was dead. More than a 

 month and twenty- four animals went into this disheartening 

 business. Obviously the disease was there, but why could he 

 not isolate the organism? 



Perhaps it was a "virus"? This is the refuse pile to which all 

 organisms are relegated, supposed to be present but too small 

 to be seen with the microscope. Wherry knew how to get 

 answer to this question. Twelve years before he had calculated 

 and shown how, if so small, they went through filters of speci- 

 fied pore size; how if not, they stayed behind, were large 

 enough then too, to lie within the visible range. He tried to 

 filter his unseen organism and found it not to pass. 



Clearly something else was wrong. He had not discovered 

 the right nourishment, he said. So out of Musgrave's and his 

 own experience he recalled the virtues of eggs. On such diet — 

 variously styled, to be sure, to get away from the too-simple 

 restaurant designation — Wherry now grew out the causal 

 agent of his death-dealing disease, succeeding at the same time, 

 by modification of the existent methods of staining, in making 

 it readily visible under the microscope. It was a little bacillus, 

 so short that it commonly looked round, with a capsule cover- 

 ing it like a halo. Besides this description [47] Wherry brought 

 forth some further facts. He reported: 



We kept the virus going chiefly by rubbing a little spleen pulp 

 into a scratch on the abdomen of animals. Simply dipping a 

 fine needle into the spleen of a dead animal or into a culture 

 and pricking the ocular or palpebral conjunctiva of rabbits 



