Smith. Perhaps I will not stay much longer but even then I 251 

 will get back too late to see you before you go East. I have 

 found no new cases and think I will be through with the three 

 I am treating in a few days. Perhaps I could add more cases to 

 the list by returning to Cinti. Mother writes as though there 

 were some at home. . . . Tell her I will get the belts & purses 

 she suggests. I am going to have a silver door-plate made for 

 Dr Sozaya to put on the room he has set aside for us foreign 

 workers — guest laboratory. Well, it is 3 P M & I must 

 hurry to the bank and get this in the Correo. 



Wherry came out of Mexico with the accounts of fifteen 

 further instances of typhoid fever to add to his Cincinnati list, 

 scientifically proved to be such and young enough in the run 

 of the disease to make clear the value or valuelessness of his 

 vaccine therapy. The whole story was published shortly [73]. 

 He compared the results of treatment with his formaldehyde 

 detoxicated vaccine in twenty-eight cases with the fate of 

 sixty-eight "controls" treated according to Hoyle. Through- 

 out his series: 



the course of the disease had been shortened, the temperature 

 uniformly showing a tendency to drop to normal after the 

 seventh or eighth dose and then coming to normal by irregular 

 lysis. The average duration of the fever in the treated cases was 

 27.5 days, in the controls, 39. The incidence of complications 

 seemed decreased — seven percent in the treated, thirty-six 

 percent in the untreated. Convalescence was shortened . . . 

 The death rate decreased from ten percent for the untreated, 

 to zero for the treated. 



BEFORE this report, two others on practical vaccine 

 therapy had appeared [71, 72], Underlying his successes 

 were principles. 



His experimental findings and his scientific abstractions had 

 increasingly moved the locus of immunity from a position 

 somewhere "in the blood," to where it really belonged — the 

 tissues themselves. Tissue immunity was the essential thing! 

 The appearance of "immune bodies" in the blood was just the 

 consequence of its sewering them out. 



