2oR interested in a streptococcus which he had isolated by Rose- 

 now's method from the root of a tooth extracted from a 

 dementia praecox case. The first subcultures when injected 

 into rabbits produced death with marked congestion of the 

 cerebral cortex; subcultures failed to kill or produce such 

 lesions. He thought he was getting improvement with a vac- 

 cine. Rabaud believes that there is a disturbance of internal 

 secretion in these cases and in one or two has noted improve- 

 ment after implanting testicular and thyroid grafts from 

 monkeys. Recent work by someone has shown that monkey's 

 blood falls into three groups — two common & one uncommon 

 — and he thought that the failure of grafts might be due to 

 using tissues from monkeys of the wrong blood group. At 

 any rate he is going to make his next grafts from a monkey 

 with homologous blood grouping. Rabaud struck me as an 

 up-to-date clinical practitioner and investigator. By the way, 

 he says that the only intestinal antiseptic is argyrol by mouth, 

 liquid, or in keratin coated capsules — "harmless in any 

 amount." I'll give you another clinical tip which may help 

 you. I got a bad attack of eczema before leaving Manila and 

 could not get rid of it until I got hold of some "bile salts." 

 The attack was accompanied by liver disturbance character- 

 ized by incomplete digestion of fats — just as in the cases 

 Tashiro & I treated at home. This is the only time that any- 

 thing I have discovered has benefited me. 



What Wherry here referred to was the outgrowth of his 

 knowledge of the effects of intestinal putrefaction; and Shiro 

 Tashiro's, of the antifermentative activities of the bile salts. 

 The two believed certain eczemas to be the peripheral mani- 

 festations of a lowered liver function, failing at times to 

 "detoxicate" poisons produced in the gut. Wherry had always 

 wished that his name might be joined with Tashiro's on a 

 paper. He got his wish [79], 



The years-old eczema of a medical student who showed too 

 few bile salts and too many fatty acid crystals in his stools had 

 been taken as indication of a liver inadequacy. Bile salts by 

 mouth, up to a grain three times daily, were given. The boy 

 was cured in a week, to convert himself into a guinea pig for 

 the benefit of medical congresses. Presenting himself as a 



