clinical subject at their opening, he would reexhibit himself 269 

 at their close as cured — having taken bile salts in the interim. 

 Wherry and Tashiro detailed the histories of five such cases 

 with "others" announced for subsequent report. 

 More therapeutic instruction followed : 



I forgot to mention this yesterday — if the pyelitis in your 

 patient is due to B coli or a related organism, try my method 

 of treatment. You know that I found out in test tube experi- 

 ments that whereas B coli is quite resistant to acriflavin alone 

 or hexylresorcinal alone, it is killed in high dilution of their 

 mixture — or when weakened by one is killed by the other — 

 same principle as a heart blow followed immediately by an 

 upper cut. On this basis I cured a child on the pediatric service 

 that had had coli pyelitis for months & been on hexylresorcinal 

 without benefit. Later I cleared up two cases of coli cystitis; 

 I gave one grain of acriflavin (keratin coated pills or capsules) 

 every four hours for 2—3 days until the urine was strongly 

 fluorescent; and then started (continuing the acriflavin) with 

 5 grains of hexylresorcinal every four hours for a day or two. 

 In one of the latter, the patient felt badly after 24-3 6 hours 

 of the combined therapy and treatment was stopped; never- 

 theless on the next day the urine had cleared! Adios! 



Though separated from his appendix, Wherry maintained 

 that the operation had been unnecessary. He was "sensitive," 

 he said, to some of his intestinal flora and had suffered an 

 "asthmatic" cramp of the involuntary muscles of his lower 

 bowel. He convinced even E C Rosenow that he would have 

 gotten well anyway if only they had given him sugar. The 

 latter wrote to Marie (August 2, 1930) : "Tell Will that Dr 

 W J Mayo has stated that in obscure abdominal conditions 

 resembling appendicitis, the cause may be an intestinal allergy, 

 quite as he surmised." Rosenow continued this letter in more 

 personal fashion, making some notes that one day may be of 

 medico-historic interest: 



. . . Just received a letter from Dr Plotz at the Pasteur insti- 

 tute telling me of the isolation in pure culture of a diplo- 

 streptococcus corresponding to the one I have repeatedly 

 isolated from the spinal fluid in cases of poliomyelitis. I think 

 I told Dr Wherry of seeing a case of polio at the congress in 



