118 Essays in Biochemistry 



able, it seems plausible to assume, as was suggested some years ago, 1 '- La 

 that the coupling between the energy-yielding processes of the cell and 

 the synthesis of the peptide bonds of proteins may be funneled through 

 a relatively small number of amides or peptides such as glutamine or 

 glutathione. At best, this view can still be considered only a working 

 hypothesis. However, it seems a useful concept in attempting to 

 discern new experimental approaches to the difficult task of elucidating 

 the chemical pathways in the biosynthesis of peptide bonds. 



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