Glycogen Turnover 



301 



— P - 3— |— P - 2-f-P - 1-| 



Fio. 4. Schematic representation of the tierwise degradation of a glycogen 



molecule. 



In order to gain insight into the time course of the distribution of 

 isotope in glycogen, studied by this technique, samples of glycogen 

 from rat carcass and liver, which had previously been studied by the 

 /^-amylase method, were reinvestigated. These samples were derived 

 from rats which were killed 6, 12, 24, and 48 hours after intraperitoneal 

 injection of glucose-C 14 . The results of these studies are summarized 

 in Tables 4 and 5. 



Table 4. Relative Specific Activity in LD (Phosphorylase) from 

 Rat-Carcass Glycogen 



Table 5. Relative Specific Activity in LD (Phospborvlase) from 

 Rat -Liver Glycogen 



At each point in time studied, rat-carcass glycogen bore certain 

 similarities to rabbit-muscle glycogen described above. The relative 



