ERNST G. HUF 



217 



added (without reducing XaCM correspondingly) to give K"*" levels ranging from 

 approximately 0.1-20 ;uEq ml. The same kind of solution was used at the two 

 sides of the skin. All experiments were carried out at 25°C. 



• 73 exp.j y = -0.90X + 2.42; r - -0.996; P - <0.0I 



= -0.88X + 2.85; r -. -0.980; P = <0.01 



- -0.95X + 3.28; r: -0.993; P = O.Ol 

 213 Controls 



[no*] : 169.3 peq/ml 

 [nq*] = 119.3 fjeq/ml. 



[no*] : 47.9/ueq/ml 



loq[K-] 



-I 



■0 5 



5 



+ I 



■2 



Fig. 8. Dependence of log ([K+]i/[K+]e) (intracellular/extracellular potassium concentra- 

 tion) on log of [K+]e for three extracellular sodium levels. Rana pipiens (29). 



With reference to the question, in what physico-chemical state may potassium 

 be said to be in skin, the following can be pointed out : if one plots, as has been 

 done in tigure 8, the log of the extracellular K+ concentration, [K+]e, on the 

 abscissa against the log of the ratio of the intracellular K+ concentration, [K+]i 



