424 



CLEMENTE AND RICHARDSON 





ITF"-^ ^'^v^'.tT^f^ 



•,^ ^^ 



s./> 





\ 







^ ^ '1 





B 





Vh,. 7. Set lions of cerebellum in idls administered 12,5UU rad alpha particles. 

 (A.) Rat sacrificed 7'/; weeks after radiation. Note the spongy degeneration of the 

 cerebellar cortex. X 63. (B.) Higher power view of cerebellar surface pictured in 7A, 

 showing degenerative vacuolization, miningeal thickening, and vascular hyalinization 

 (arrows). X 360. (C.) Another rat 10 weeks after radiation. Note the greatly thickened 

 surface cerebellar vessels. X 175. (D.) High power view of cerebellar cortex in rat 

 described in 7C. Note the extensive Purkinje cell loss just under the cerebellar molecu- 

 lar layer. One pyknotic cell (arrow) still remains while a few nuclei of other vacuolized 

 Purkinje cells can also be seen. X 500. 



