GENERAL INDEX 



Acetate, utilization by cells of Streptoiuyces 



griseus, 150 

 Acid 



production, 157, 158 



reaction of Streptomyces gi'iseus, as affected by 

 metals, 141 



utilization, 158 

 Actinomyces, historical significance of name, 52 

 Actinornycetales, classification and description, 56, 



65 

 Actinomycetin, action on bacteria, 173, 174 

 Actinomycins, production and properties, 203, 231 

 Actinomycosis, 1, 7, 47, 251, 257 

 Actinophage 



effect on 



Antino))tycetales , 181 

 plaque formation, 176 

 streptomycin production, 176, 177 



isolation from soils, 179, 180 



mechanisms, 175^181 



production, 175 

 Actinorhodin, 205 

 Actinorubin, 142 



Adaptation to antimicrol)iul agents, 109 

 Aerobic actinomycetes, metabolism, 129, 130 

 Aldolase, 189 

 Alginase, 188 



Allergies caused t)y acinomycetes, 263 

 Amino acid 



content of cell walls, 162, 163 



synthesis, 163 

 Amylase 



hydrolysis of mannosidostreptomycin, 187 



production, 187 

 Anaerobic actinomycetes, metabolism, 131, 149 

 Antagonisms in mixed pojiulat ions 



forced, 209 



types, 207 

 Antagonistic organisms 



isolation from natural substrates, 211. 213, 215 



soil as source, 209, 211-215 

 Antagonistic properties 



antiphage, 219 



bactericidal, 208, 218 



distribution among actinomycetes, 210, 213 



effects on pathogenic organisms, 209, 211, 216- 

 218, 220 



of fungi and bacteria, effects on actinomycetes, 

 221 



fungicidal, 208, 209, 215-218, 220 



relation to pigmentation, 217 



screening methods to determine, 212 

 Anthocyanins, 200, 201 

 Antibacterial substances 



as chemotherapeutic agents, 208 



j)roduction by organisms, 207, 208 

 Antibiotic -producing organisms 



activity of soil actinomycetes, 211-215 



isolation and testing 226, 227 



mutations caused by irradiation, 107 



variants, 105 

 Antibiotics 



activity against pathogens, 241 



antiphage activity, 24, 219 



antiprotozoan, 240 



antitumor, 240 



antiviral, 219, 240 



autoantagonisms, 222, 223 



bactericidal, 216 



biosynthesis, 163, 241, 242 



chemical structure, relation to activity, 242 



classification, 204, 229 



concentration, effect on resistance, 238, 239 



effect 



of metals on production, 142, 145 



of phages on production, 177, 178, 181 



historical studies on production, 14 



identification by bacterial stains, 240 



isolation and testing methods, 211 



media for production, 229 



])rinciples of production, 225 



production in natural substrates, 45, 221 



properties, 207 



screening programs, 211, 217, 241 



spectra, 228 230, 241 



test organisms, 218, 219 

 Antifungal action, 197, 232 

 Antigenic properties, 166-167 



Antimicrobial activity of strcptomycetes, as af- 

 fected by metals, 142 

 Antimicrobial spectra of Sircploiiiyccs frculiae 



strains, 237 

 Antiphage f:ictors, 24, 219 



322 



