( J EN ERA L IM)i;.\ 



323 



Atililumor acti\il\ of ;icl iiuniiycclcs, 'Jl'.t. "JIO 

 Aiyl suir;i(;is(' inodiict inn , liH, I'.I'J 

 Aiiroothriciii, Jil") 

 Aiit.)itilnl.iti..ii. 222, 221. 227 

 Aiildl.v -i- 



nu'rh;iiiisins, KiS 



rohitioii to antibiotic produi'l ion, 171 

 Autot rojiliN-, ]M) 



!?ij production. s(( \'it:iiniri ]^^: ])i'odiict ion 



Bacteria, relation to act inoni^cotcs, 1, 13, o-i, 71 



Bacteriol.Nsi.s, mechuni.sms, 171 



Biochoniist r\'. historical studios, 14 



Bioiofiw historical studies. 11 



Biotin piHxluction 1)>' SlrcptoiHi/ccs oZ/raccj/.s, 194 



Bromtet racydine. 14.") 



Cancer, actinoniycins in treatment. 203 

 Candicin, production as affected by metals, 142 

 Carbohydrate composition of cell walls for taxo- 



nomic use, 160 

 Carbomycin, 238 

 Carbon-dioxide fixation by anaeroliic actinomy- 



cete.s, 149 

 Carbon sources, utilization 

 agar, 125 



by antibiotic producers, 122, 123 

 as basis of classification for antibiotic-jjroducing 



streptomyces, 121 

 cellulose, 124 

 chitin, 125 



efficiency and metabolic changes, 125 

 glucose, 132, 133 

 of proteins, 124 

 relation 



to nitrogen utilization, 128 

 to streptomycin ])roduction, 119, 133 

 in species characterization, 119, 120 

 unusual compounds, 125 



by various actinomycetes, 118, 120, 122, 123 

 Carotinoids, 193, 202 



Catalase activity, relation to streptomycin pro- 

 duction, 190 

 Cell walls, chemical comjjosition, 158 163 

 Cellulase production, 188 

 Cellulose decomposition, 155, 244 

 Chitin decomposition, 155 

 Chitinase production, 186 

 Chloramphenicol, production and properties, 145, 



236 

 Chlortetracycline, production and i)roperties, 145, 



164, 237 

 Cholic acid utilization, 152 

 Chromopars, 199 

 Chromophores, 199 



( 'l.-issilicnt ion systems 



cailion utilization by st rept oin\ces, 20, 201 



cell wall comixjsit ion, ()!l 



Buchanan's. 56 



geneiic, 47 



grouj) characteristics, 67-70 



gioup identification by sporulation, 67 



historical background. 55 



l)igmented antibiotics, 204 



specific, 4!) 

 Club formation, 7, 81 

 Coelicolorin, 205 



Coenzyme A profluction, 192, 195 

 Colony 



formation, 8, 76 



variants of Streplotni/ccs griscus, 96 

 Constancy of characters, 95 

 Coremia formation, 80, 84 

 Cortexone conversion, 152 

 Crop yields in relation to actinomycete population 



of soil, 33 

 Cross-resistance, 222, 223 



Cultivation of actinomycetes, technicjues, 17 

 Cultural variations, 103 



Decomposition of plant materials 

 cellulo.se, 155, 244 

 complex, 247 



hemicellulcses, 155, 244, 246 

 humus, 247 

 lignin, 244, 247 

 polysaccharides, 244-246 

 proteins, 245 



thermophilic composts, 248 

 Deguanidases, 186 

 Diasta.se production, 185 



Diketopiperazine, effect on rice germination, 196 

 Diseases 

 of animals 



actinomycetes isolated from, 252-257, 262 



actinomycosis, 7, 251-253, 257 



allergic reactions, 263 



mycetoma, 261, 262 



nocardiosis, 261, 263, 264 



therapy, 263 

 causation, 6, 13 

 of plants 



caused by chromogenic organisms, 275 



citrus gummosis, 275 



mangel scab, 274 



necrosis of seedlings, 275 



])otato scab, 7, 265-274 



strawberries, 275 



sugar beet scab, 274 



sweet potato j)ox, 275 



