XVUl CONTENTS 



Page 



b. Antibody Against Nucleic Acid-Hydrolyzing Enzymes of 

 Snake Venom 330 



c. Inhibition of Ribonuclease by Homologous Anti-Serum 330 



2. Neutralization of the Toxic Action of Crystalline Urease by Its 

 Homologous Antibody 331 



3. Antibody Against Penicillinase 332 



J. Immunity Against the Enzymatic Activities of Bacterial Toxins 335 



1. Bacterial Toxins 335 



a. Type A Toxin oi Clostridium hotulinum 335 



b. Biological Action of Botulinus Toxin 336 



c. Crystalline Tetanal Toxin 336 



d. Enzymatic Activities of the Toxins of Vibrio Comma . 337 



2. Types of the Toxins of Clostridium- Oedematiens .... 338 



3. Lecithinase of Clostridium. Welchii 339 



a. Classification and Properties of the Toxins of Clostridium 

 Welchii 339 



b. Preparation of Toxins 342 



c. The Lecithinase Activity of the Toxin 342 



d. Characteristics of Lecithinase 345 



e. Quantitative Methods Used for the Measurement of Leci- 

 thinase Activity 345 



f. Phenomenon of Opalescence in Serum and Lecitho-Vitellin 

 Produced by the Action of the Toxin of CI. Welchii . 347 



g. Production of Opalescence in Serum and Lecitho-Vitellin 



as a Measure of the Potency of the Toxin 349 



h. Lecithinase Activity as a Measure of Biological Effects of 



Toxin 350 



4. Immunity to the Pharmacological Actions of Toxins 352 



a. The Inhibition by CI. Welchii Toxin of the Oxidation of 

 Succinate by Tissue 352 



b. Neutralization of the Inhibition of Tissue Respiration by 

 Toxin as a Measure of the Antitoxin Concentration of Im- 

 mune Serum 354 



c. Pharmacological Activity of the Toxins of CI. Welchii 355 



5. Action of Antitoxin on Enzymes Causing Histological Changes 



in Gas-Gangrene 357 



PART V 

 ANTIBODIES AGAINST RESPIRATORY ENZYMES 



A. Respiratory Enzymes 363 



1 . Dehydrogenases, Flavoproteins, Cocarboxylase Containing En- 

 zymes, and Heme Containing Enzymes 363 



