1 74 IMMUNO-CATALYSIS 



According to them the end chains of the globulin molecule can be 

 uncoiled by a denaturing agent or condition, and during the process of 

 recoiling, antigenic substances may intervene and impress their con- 

 figurations on the recoiling end chains, yielding specific "antibodies." 

 A similar experiment has been carried out by Bacon (1943) whereby 

 whole plasma was dehydrated from the frozen state in the presence 

 of an antigenic substance. The above investigators claimed to have 

 obtained specifically reactive final "antibody" products. While none 

 of these investigators have since produced additional corroborative 

 results, as it was discussed earlier (page 116), various investigators 

 have repeated these experiments and failed to confirm the above results. 



