ANTIBODIES AGAINST RESPIRATORY ENZYMES 



365 



protein yielding leucoflavoprotein. The latter reacts with an oxidizing 

 system, oxygen directly, or through the mediation of the cytochrome- 

 cytochrome oxidase system which constitutes a terminal oxidizing 

 system.* 



2. Enzymes Involved in the Fermentation and Oxidation 

 of Glucose (Phosphorylation of Hexoses and Oxidation- 

 Reduction Reactions of Hexose-Breakdown Products) 



GLYCOGEN (or Starch) 



(O 



+H3PO4 



+Phosphorylase (-f AMP) 



CHO— PO3H2 

 CHOH \ 



CHOH 



CHOH 



I 



CH 



O 



CHoOH 



Glucose- 1 -phosphate 



II -[-Phosphoglucomutase 



4-Mg+ + ,Mn+ + ,orCo+ + 



(2) 



Glucose 

 ATP 



Mg++ T ' 



Hexokinase (3) 



CHOH 



I \ 



CHOH 



CHOH 



CHOH 

 I 

 CH 



Phosphatase 



O > 



(4) 



Glucose 4-H3PO4 



CH2-O-PO3H2 



Glucose-6-phosphate 



*For a comprehensive discussion of respiratory enzymes the reader is referred to: 

 A Symposium on Respiratory Enzymes (1942), The University of Wisconsin Press; 

 C. Oppenheimer and K. G. Stem (1939); and Sumner and Somers (1947). 



