542 



IMMUNO-CATALYSIS 



Protein(s), conjugated— (Cowt'ci) 

 antigenic specificity of, 84 

 determinant groups in, 84-86 

 denaturation by iodination, 200 

 determinant structures in, 115 

 foreign, 53 



resistance to host enzymes, 53- 

 54, 63 

 formaldehyde, action on, 196 



reversibiUty in vivo, 208 

 heme enzyme, specificity of, 83 

 "hving," 180-183 



resistance to proteinases, 183 

 metabolism of, 51-57 



foreign versus species specific, 



comparison, 52-56 

 dynamic equilibrium in, 52 

 ocular lens, 51 



species specificity of, 51 

 reactive groups in, 195 

 side groupings in, 79 

 acidic, 80 

 basic, 80 

 hydrophobic, 82 

 polar, 81 



relation to biological activity, 79 

 species specific, 53 

 synthesis, 76 

 thiol groups in, 79 

 "Proteinogen," 106 

 Proteus vulgaris, oxidation of amino 



acids by, 374 

 Prothrombin, 276, 279, 289 



conversion into thrombin, 279, 289 

 by trypsin, 279 



by snake venom, 289, 290-291 

 Protons, solvated, 13 

 Protolytic reaction, 14 

 Purines, oxidation of, 170-173 

 Pyridoxal, 376 



phosphate, 376 

 Pyridoxamine, 376 

 Pyruvic acid, 368, 371, 372 

 dehydrogenase, 364, 371 



(enol)-phospho-, 367, 369, 373, 

 419 

 enolase, 367, 371 

 ketolase, 364 

 reductase, antibody against, 381 



Quinidine, as d-active catalyst, 127- 



129 

 Quinine, as 1-active catalyst, 127-129 



R 



Racemization, 19, 23 

 Raffinose, 152, 186 

 Red blood cells, 188 



adsorption of toxins on, 188 



agglutination by ricin, 315, 316 



hemolysis by snake venom, 307- 

 310 

 Rennin(s) 



activity, 30, 303-307 



antibody against, 304-307 



crystalline, 26, 304 



milk clotting properties, 303-304 

 Resonance, quantum-mechanical, 1 5 

 Resistance to drugs, 100, 103 

 Reticulin, 357, 360 

 Reticulo-endothelial cells 



antibody formation in, 72-73 



plasma cells and, 74-77 

 Reticulo-endothelial theory, 72-73 

 Rhizohiuni radicicolum, 237 

 Riboflavins 



monophosphate, 363 



adenine dinucleotide, 363 

 Ribonuclease, d-, 106 



antibody against, 330-331 



complex with tobacco mosaic virus, 

 185 



crystalline, 26 



desoxy-, crystalline, 27 

 Ricin 



agglutination of red blood cells by, 

 314 



affinity for red blood cells, 316 



