386 V. BLOOD LIPIDS 



Small amounts of gangliosides were likewise present. Klenk and Wolter 205 

 confirmed the results of Yamakawa and Suzuki 203 concerning the occurrence 

 of the ganglioside type of glucolipids, the so-called hematosides, in the 

 stroma of the horse. Neuraminic acid (presumably identical with pre- 

 hemataminic acid) was found to be present, while hexosamine was absent. 

 An unsaturated acid, possibly nervonic acid, was also found to occur. 



b. Lipids in Leucocytes. An examination of the lipid composition of 

 the white blood cells of women has been made by Boyd. 92 The average 

 values for the white cells (expressed in milligrams per 100 g.) in the case of 

 the eight women subjects examined, together with the standard deviation, 

 are as follows: total lipid, 1710 ± 734; neutral fat, 536 ± 536; total fatty 

 acids, 1103 ± 614; phospholipid fatty acids, 534 ±170; cholesterol ester 

 fatty acids, 73 ± 65; neutral fat fatty acids, 508 ± 508; total cholesterol, 

 300 ± 60; free cholesterol, 194 ±110; combined cholesterol, 110 ± 97; 

 and phospholipids, 802 ± 255. The comparative composition of red cells 

 and of polymorphonuclear leucocytes of rabbits is given in Table 8. 



Table 8 

 The Comparative Lipid Composition of Red Blood Cells 

 and of the polymorphonuclear leucocytes of rabbits" 



Per cent total lipid 



Average content, mg. % 



L:E Leuco- Erythro- 



Lipid component Leucocytes Erythrocytes ratio cytes cytes 



Neutral fat 530 ± 130 41 ± 18 12.9 30.2 8.5 



Total fatty acids 1140 ± 100 230 ± 18 4.96 64.6 47.6 



Cholesterol, total 243 ± 10 146 ± 3 1.66 13.8 30.2 



ester 9 ± 2 0.5 



free 234 ± 10 146 ± 3 1.60 13.3 30.2 



Phospholipids, total 950 ± 40 264 ± 8 3.60 53.9 54.5 



Cerebrosides 41 ± 30 33 ± 8 1.24 2.3 6.8 



Distribution of 

 phospholipids 



Monoaminophospholipids . . 670 ± 30 212 ± 9 3.16 70.6 80.4 



Lecithin 300 ± 30 94 ± 5 3.19 31.6 35.6 



Cephalin 370 ± 20 118 ± 7 3.14 39.0 44.8 



Sphingomyelins 280 ± 10 52 ± 2 5.29 29.4 19.6 



a N. S. Burt and R. J. Rossiter, Biochem. J., 46, 569-572 (1950). 

 (4) Interrelations between Blood Lipids 



Although considerable variations may obtain, under physiological con- 

 ditions, in the absolute amounts of the several blood components, there is a 



206 E. Klenk and H. Wolter, Z. physiol. Chem., 291, 259-265 (1953). 



