FACTORS ALTERING CONCENTRATION OF BLOOD LIPIDS 



413 



evidence which was accumulated during the past forty years has consistently 

 shown that the ingestion of fat causes a moderate but definite concomitant 

 rise in phospholipids. Reicher 339 reported an increase of 32% in blood 

 lecithin after fat feeding; this was greater than the rise in the neutral fat 

 fraction. Other workers likewise obtained higher phospholipid values in 

 blood serum after fat feeding, although these increases were less 

 marked. 89 ' 90 ' 345 - 348-350 Jacobson and co-workers 347 reported that the inges- 

 tion of fat by newborn calves is followed by an increase in blood phospho- 

 lipids. Bloor alone, 223 and in collaboration with Gillette and James, 225 



Fig. 4. Serum fatty acids after the ingestion of a meal containing 3.4 g. 

 to 4.0 g. of fat per kilogram body weight, in the form of cream and butter. 

 The 3 top curves represent the maximum, average, and minimum responses, 

 respectively, of total fatty acids, while the lower 3 curves show the corre- 

 sponding data for the phospholipid fatty acids. 202 ' 345 



reported that an increase in blood lecithin occurred in the plasma after 

 fat feeding. An increase in the lecithin in the blood corpuscles was ob- 

 served by Knudson 89 and by Bodansky. 90 Wendt 351 found that the increase 

 in phospholipids occurred only in the plasma, and that the red blood cells 

 took no part in the response to the feeding of neutral fat. Artom and Ped- 



348 1. Bang, Biochem. Z., 91, 104-110 (1918). 

 349 W. Hueck and L. Wacker, Biochem. Z., 100, 84-99 (1919). 

 "> T. F. Zucker, Proc. Soc. Exptl. Biol. Med., 17, 89-91 (1920). 

 361 H. Wendt, Biochem. Z., 250, 212-219 (1932). 



