542 THE BACTERIOPHAGE AND ITS BEHAVIOR 



toward the different dysentery bacilli at the time of the administration 

 of the bacteriophage suspension. It is evident that in routine practice 

 it would not be necessary to investigate all these points, especially 

 since the administration of the bacteriophage is always inoffensive. 



In each of the following cases the only treatment instituted has been 

 the ingestion of the bacteriophage. 



Robert K (eleven years). This was a case of bacillary 



dysentery of moderate severity with from 5 to 7 bloody stools a day. 



August 1. The stool examination showed: B. dysenteriae Shiga 

 present. 



The intestinal bacteriophage with virulences as follows: B. coli ++, 

 Shiga 0, Flexner 0, Hiss 0. 



August 2. At 10 o'clock in the morning the patient ingested 2 cc. 

 of a Shiga-bacteriophage. This filtrate had been held for thirty-five 

 days. During the afternoon of this day there were 3 bloody stools, in 

 the evening there was one stool and that was free of blood. 



August 3. During this day there was only the one formed stool. 

 Examination showed: B. dysenteriae Shiga absent. 



The intestinal bacteriophage with virulences as follows: B. coli 

 -f + + +, Shiga + + + +, Flexner + + +, Hiss + + +• 



August 8. The intestinal bacteriophage was active as follows: B. coli 

 + + + , Shiga +, Flexner 0, Hiss +. 



August 9. The patient was discharged from the hospital. 



Andre B (ten years). A case of bacillary dysentery of 



moderate severity. During the period from August 25 to 29 inclusive 

 there were 9 to 11 bloody stools a day. 



August 28. Stool examination showed: B. dysenteriae Shiga present. 



Intestinal bacteriophage active as follows: B. coli +, Shiga 0, Flexner 

 0, Hiss 0. 



August 29. At 4 p.m. the patient ingested 2 cc. of a Shiga-bac- 

 teriophage suspension which had been prepared for 2 months. 



August 30. There was one bloody stool in the morning and during 

 the afternoon and the night there were 5 stools, none of which showed 

 any blood. 



August 31. There were 3 fluid, but not bloody, stools. 



Examination showed: Shiga bacilH not present. 



The intestinal bacteriophage active as follows: B. coli + + + +, 

 Flexner ++, Hiss + + + , Shiga + + -f + . 



