SPECIFIC THERAPY WITH BACTERIOPHAGE SUSPENSIONS 543 



September 1. There was one fluid stool, without blood. 



September 2. There was one fluid stool, without blood. 



September 3. There was one formed stool. Examination of the 

 intestinal bacteriophage showed: B. coli + ++, Shiga + + + +, 

 Flexner + ++, Hiss +. 



September 8. Reactions with the intestinal bacteriophage were: 

 B. coli ++, Shiga 0, Flexner 0, Hiss +. 



September 9. The patient was discharged from the hospital. 



Robert D (twelve years). This patient had a very severe 



dysentery, with vomiting, cold sweats, chilhng of the extremities, and 

 involuntary and uncountable stools. 



September 8. The stools could not be counted. They were fetid, 

 purulent, and streaked with blood. Examination showed: B. dysen- 

 teriae Shiga present; about 1 out of every 10 colonies on the plates was 

 the dysentery bacillus. 



The intestinal bacteriophage showed no virulence for B. coli, or for the 

 Shiga, Flexner, or Hiss organisms. 



September 9. Two cubic centimeters of a suspension of Shiga-bac- 

 teriophage were ingested at 11 o'clock. This suspension was three and 

 one-half months old. During the afternoon and the night the stools 

 became less numerous but continued bloody. 



September 10. There were 6 fluid stools, without blood. Examina- 

 tion showed: 5. dysenteriae Shiga, not present. 



Intestinal bacteriophage active as follows: B. coli + + + +, Shiga 

 + + ++, Flexner + + + +, Hiss + + + . 



September 11. There were 2 normal, formed stools. 



September 20. The patient was discharged from the hospital. 



Juhen D (three and one-half years). This was a case of 



very severe dysentery. The general condition of the patient was very 

 bad. A sister of the patient had died at home of dysentery on Sep- 

 tember 8. 



From the 11th to the 13th of September the number of stools, all of 

 which were bloody, could not be counted. 



September 13. The patient entered the hospital. Examination 

 showed : B. dysenteriae Shiga present, the dysentery bacilh constituting 

 about 4 of every 5 colonies on the plates. 



The intestinal bacteriophage was without activity for either B. coli 

 or the dysentery organisms. 



