544 THE BACTERIOPHAGE AND ITS BEHAVIOR 



September 13. The patient ingested 2 cc. of Shiga-bacteriophage at 

 5 o'clock. This filtrate had been prepared for fifteen days. 



September 14. There were 6 bloody stools. The intestinal bacterio- 

 phage showed virulences as follows : B. coli + + + , Shiga + -1- + , Flexner 

 + + , Hiss +. 



September 15. During the day there was one bloody stool. There 

 were also 5 stools without blood. Examination showed: B. dysenteriae 

 Shiga absent. 



The intestinal bacteriophage with activities as follows: B. coli 

 -f-F + + , Shiga + + + + , Flexner + + + , Hiss + + + . 



September 16. There were 4 stools, all without blood. The intesti- 

 nal bacteriophage showed : B. coli + + + , Shiga + + + + , Flexner + + , 

 Hiss + + + . 



September 17. During the day there were one fluid stool and 2 

 formed stools. The intestinal bacteriophage showed: B. coli + + + +, 

 Shiga + + + + , Flexner + + , Hiss +. 



September 18. There were 2 formed stools. The intestinal bacterio- 

 phage was virulent as follows : B. coli + + + + , Shiga + + + + , Flex- 

 ner + , Hiss + + . 



September 2G. The patient was discharged from the hospital. On 

 this date the virulence of the intestinal bacteriophage was: B. coli 

 + + + , Shiga 0, Flexner 0, Hiss +. 



Emile D (seven and one-half years). This patient was a 



brother of the preceding case, and showed a very severe dysentery. On 

 the 11th and 12fch of September there were 20 to 25 fetid stools, fluid but 

 not bloody. 



September 12. Examination showed that the Shiga bacilli were 

 very abundant. The intestinal bacteriophage was inactive for B. coli 

 or for the dysentery organisms. 



September 13. There were 25 bloody stools. At 5 o'clock the pa- 

 tient ingested 2 cc. of bacteriophage suspension which had been pre- 

 pared 6^ months previously. 



September 14. There were 4 bloody stools in the morning and 2 

 stools without blood in the afternoon. Examination of one of the latter 

 showed no Shiga bacilli. The virulences of the intestinal bacteriophage 

 were: B. coli + + + + , Shiga + + + + , Flexner + + , Hiss + + + . 



September 15. There were 5 stools, all free of blood. 



September 16, 17, and 18. During these days there were 3 or 4 stools 

 a day. None of these contained blood. 



