570 



THE BACTERIOPHAGE AND ITS BEHAVIOR 



examination showed nothing in the way of organisms, and the culture 

 made from it failed to yield a growth. Some of it was inoculated into 

 a guinea pig, and the guinea pig is still alive as this is written (10 days 

 later). The aspirated material, examined for bacteriophage, showed 

 that it was present, with a very high virulence for B. pestis (+ + ++). 



On the 25th both of the buboes were incised very freely. Both 

 contained some purulent material. By August 8th healing was com- 

 plete, a fact of some interest in that, as we know, usually in such cases 

 the healing process is very slow, sometimes requiring a month. 



The curve showing the temperature of this patient is here given 

 (chart 22), and it may be said, that here, as in the other three cases, the 

 temperature changes closely parallel the general condition of the patient. 



Chart 22. Georges Cap Bubonic Plague 



Treatment consisted in a single injection of Pestis-bacteriophage 



Case 2. Nicolas Sw ,40 years old. Second Officer. 



The crew and passengers of the steamship, having been disembarked 

 at the Quarantine Station, four sailors, under the command of this 

 officer were left on board. During the night of July 12th and 13th, 

 he was taken with fever, chills, and had a frontal headache. On the 

 morning of the 13th he was transferred to the hospital. At 2 p.m. of 

 this same day he had a temperature of 40.2°C., a pulse of 124, irregular 

 with skipped-beats, the conjunctivae were injected, and he was markedly 

 prostrated. The right crural gland was swollen, painful, and of the 

 size of a nut. Some of the material from the gland was removed for 

 bacteriological examination. In view of the clear-cut symptoms, as- 

 sociated with the presence of a previous case of plague, 1 cc. of bac- 



