2o8 GOTTWALT CHRISTIAN HIRSCH 



Discussion 



Porter: I think it is appropriate to mention to the audience at this point that 

 Palade has been interested in this topic and has published or has in press observa- 

 tions which would indicate that the intracisternal granules do not have to enter the 

 matrix phase of the cytoplasm to get to the Golgi components, but that intermit- 

 tent continuity is made between the cavities of the ER and those of the Golgi. 

 It is probable that the granules break down into less condensed forms in making 

 this migration. 



