PREFACE y 



Throughout the book standard techniques are presented, ana- 

 lyzed, and discussed. It is lioped that reference to the practical 

 application of immunological procedures will i)romote a greater in- 

 terest in the subject on the part of the student. 



The chapters on hypersensitiveness are placed last because an 

 understanding of the material contained in the chapters preceding 

 them is of material value in understanding the present theories 

 pertaining to the complex problems inherent in allergy. A great 

 deal of emphasis is placed upon the subject of specificity since it 

 plays such an important part in diagnostic tests and in passive 

 and active immunization. Since the material in many of the chap- 

 (ei's is rather condensed, the lists of references at the ends of most 

 chapters have been somewhat extended to accommodate the stu- 

 dent who desires to read more extensively about some particular 

 subject. For the convenience of the reader a synopsis of the three 

 chapters on specificity is presented in a separate chapter (XV). 



A number of colleagues, former students and friends have ren- 

 dered material assistance in the preparation of the manuscript for 

 this book. To all of them the author wishes to express his ap- 

 preciation. There is space for mentioning only a few. Among 

 these, Mr. Harold Clark deserves credit for outlining the chapter on 

 flocculation tests in syphilis, in addition to rendering help in many 

 other ways. Doctors C. M. Downs, H. R. Wahl, and Joel Wahlin 

 have criticized parts of the manuscript. Dr. Ray Brewster and 

 Mr. ]\Iorgan Rarick have rendered a great deal of assistance in the 

 preparation of the chapter on modified antigens. Four other 

 individuals whose services have made possible the completion of 

 this volume are IMiss Rosella Blood, the artist, Miss Letha Lemon 

 and Mr. Harold Nelson, secretaries, and Mr. Louis Forman, who 

 checked the bibliography. 



The author has drawn quite freely from information contained in 

 various publications. These are listed in the text, and an attempt 

 is made to give due credit to l)oth author and publisher. 



Noble Pierce Sherwood. 



Lawrence, Kansas. 



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