CONTENTS 



CHAPTEE I PAGE 



InFECTIOX and IXFKCTIOUS AGENTS ___________ 29 



Infection; Classification of Parasites; 8ymbiosis, 29; Infection 

 Without Pathological Change ; Infection With Patliological Change ; 

 Types of Pathological Changes; Localized and Generalized Infec- 

 tion; Bacteremia, Septicemia, and Pyemia, 30; Acute and Chronic 

 Infections; Focal Infections; Beneficent Infections; Specific Mi- 

 crobic Association, 31; Metastasis; Secondary Infections; Infec- 

 tious and Contagious Diseases; Toxemic Diseases; Bacterial Toxins, 

 32; Botulism; Tetanus, 33; Gaseous Gangrene; Diphtheria; Endo- 

 toxins; Phytotoxins and Zootoxins, 34; Antitoxins; Ptomaines, 

 35; Pathogenicity; Virulence; Definition of Virulence; Measure- 

 ment of Virulence, 36; Factors Altering Virulence; Relation of 

 Capsule Formation to Virulence; Hypothesis of Welch; Correla- 

 tion of Virulence and Colony Type, 37; Labile Antigens and 

 Virulence, 38; Importance of Host Factors in Determining Viru- 

 lence; Aggressins; Nature and Characteristics of Viruses, 39; 

 Chemical Composition of Bacteria, 40; Carbohydrate; Protein; 

 Effect of Environment on Bacteria; Theory of Constancy of Char- 

 acteristics, 41; Evidence of Heterogeneity Within a Culture; 

 Fluctuating Variability; Early Theories of Bacterial Character- 

 istics, 42; Relation of Environment to Size, 43. 



CHAPTER II 

 Host-Parasite Relationship _____________ 47 



Introduction; Portal of Entry, 47; Endemics, Epidemics, Pan- 

 demics; Incubation Period; Environmental, Not Involving Immu- 

 nity; Protection Due to Lack of Contact, 48; Removal of Primary 

 Host; Sanitary Measures, 49; Racial Freedom From Disease May 

 Be Due to Customs Rather Than Immunity; Effect of Customs; 

 Environmental Conditions: Absence or Presence of Factors Af- 

 fecting Immunity Mechanisms; Climate Factors; Resistance and 

 Susceptibility Factors, 50. 



CHAPTER III 



Inflammation and Leucocyte Response _________ 54 



Introduction; Acute Inflammation; Lobar Pneumonia, 54; Furun- 

 cle, 55; Chronic Inflammation — Formation of ;i Tubercle, 57; 

 Tubercle Phosphatid and Cell Stimulation; Varieties of the Tu- 

 bercle Bacillus; Development of Hypersensitiveness; Tissue Re- 

 sponse to Viruses, 59; Leucocyte Count, 60; Arneth and Schilling 

 Counts, 61; Neutrophilic Myelocytes; Juvenile Neutrophiles, 62; 

 "Stab" or Band or Rod Nuclear Neutrophilic Cells, 63; Leuco- 

 penia, 65; Leucocytosis and Increased Capillary Permeability, 66. 



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