12 CONTENTS 



CHAPTEE IV PAGE 



Anatomical and Physiological Factors in Infection and Kesistance 



OF THE Individual _________-_-__- 70 



Mechanisms of Infections, 72; Establishment Within the Tissues; 

 Eoutes of Dissemination, 74; Lymphogenous Extension, 75; Hem- 

 atogenous Extension, 76; Direct Extension; Factors Involved in 

 Pulmonary Infection; Lobar Pneumonisi,, 77; Factors Involved 

 in Intestinal Infection, 78; Ulceration of Intestine; Ulcer, Pan- 

 creatitis, Cholecystitis, 79; Appendicitis; Importance of Blood 

 Supply at Lower Orifices, 80; Factors in Genitourinary Tract 

 Infections; Cystitis, 81; Pyelonephritis; Stone in the Ureter or 

 Kinks; Acute Nephritis; Importance of Elimination; Mechanical 

 Factors of Safety; Physiological Mechanisms, 82; Prenatal vs. 

 Postnatal Immunity; Importance of Considering the Body as a 

 Whole; Underlying Principle of Therapy, 84. 



CHAPTER V 



The Eeticulo-Endothelial System ___________ 87 



Phagocytosis, 95 ; Role of Complement, 96. 



CHAPTER VI 



Natural and Acquired Immunity ____-__-_-- 102 

 Natural Immunity-^Species Differences in Immunity; Racial Dif- 

 ferences in Immunity, 102; Endocrines and Immunity, 103; Age 

 and Resistance; Vitamins and Food Factors in Resistance, 105; 

 Nutrition and Resistance, 106; Neuf eld's Theory of Phases of 

 Heightened and Lessened Resistance; Hereditary Factors in Nat- 

 ural Immunity, 107; Antibodies and Natural Resistance, 109; 

 Acquired Immunity; Immunization Against Viruses and Ricket- 

 tsiae, 110; Immunization With Attenuated Bacteria, 112; Immu- 

 nization With Killed Bacteria, 113; Immunization With Bacterial 

 Polysaccharides, 115; Whooping Cough Immunization; Immuniza- 

 tion With Detoxified Toxins, 116; Immunization Programs, 117; 

 Passive Immunity, 121. 



CHAPTER VII 



Immunity Mechanisms in Experimental Infections ______ 128 



Experimental Streptococcus Infections in Rabbits, 128; Impor- 

 tance of Antibodies; Passive Immunization With Pleural Exu- 

 - date; Experimental Staphj-lococcus Infections in Guinea Pigs, 

 129; Local Fixation; Summary of Cannon's Work on Tissue Im- 

 munity to Staphylococci, 130; Immunity to Pneumococcus Infec- 

 tion, 131; Experimental Infection of the Chorio-Allantoic Mem- 

 brane of Chick Embryos, 133; Role of Clasmatocytes in Other 

 Infections, 134; Tissue Resistance to Cysticercus Pisiformis; Re- 

 moval of Bacteria From the Blood Stream, 135; Defensive Mecha- 

 nisms in Peritonitis, 138; Defense Against Viruses; Tolerance, 139. 



