SUBJECT INDEX 



611 



American Indians, scarlet fever 



among, 102 

 Amines, role of, in infection, 74 

 Amino acids, acid and basic groups 

 of, 328 

 possible number of compounds 



from, 327 

 removal of acid properties of, 

 341 

 of basic properties of, 342 

 Anaerobes, invasive power of, in gas 



gangrene, 297 

 Anaerobic spore-forming bacteria, 



toxins of, 296" 

 Anamnestic reaction, 120 

 Anaphylactic sensitizers, definition of, 

 151 

 shock, effect of excess of liapten 

 on, 474 

 ratio of antigen to antibody in, 

 474 



Anaphylactoid reactions, 306, 307, 



489 

 Anaphylaxis, acute shock in guinea 

 pig, 477 



and tuberculin allergy, possible ex- 

 planation of dissimilari- 

 ties, 526, 527 



antitryptic index and, 477 



Arthus phenomenon, 471, 480 



bacterial systemic vs. skin sensi- 

 tivity, 525 



Bally 's blanching reaction in rab- 

 bits and, 479 



canine, 480, 481 



carbohydrate haptens and, 474 



chickens and, 484 



criteria of, 485, 486 



crop reaction in, 484 



Dale phenomenon in, 478 



desensitization, 476 

 with histamine, 494 



discovery of, 470 



duration of sensitization, 474 



early studies of, 470 



effect of endothelial blockades on, 

 490 

 of trypan blue on, 490 



embryonic chick and, 484 



evidence favoring H-substance, 493 



feline, 481 



frogs and, 483 



further discussion of physical the-^ 

 ory of, 494 



guinea pig, 477 



histaminase in, 494 



histamine theory of, 493-497 



Anaphylaxis — Cont 'd 



H-substance and, 493-497 

 incubation period in active, 473 

 liver and, 490 

 man and, 485 



Manwaring's tlieory of, 490 

 mechanisms of reaction, 492 

 metabolic changes in shock, 487 

 monkeys and, 484 

 nature of, 488 



of sensitizing antibody in, 486 

 passive sensitization, 472, 475 

 permeability change in, 491 

 protection of drugs in, 477 

 protracted, in guinea pig, 478 

 rabbits and, 479, 480 

 rats and, 482 

 refractory state, 476 

 reversed, 480, 484 

 Richet and Portier's work, 471 

 role of trypsin in, 476 

 sensitizing dose in, 473 



substance, 472 

 serum sickness and, 312-314 

 shocking dose of antigen, 474 

 )Simond's work on, 492 

 simple chemical compounds and, 



472, 473 

 site of reaction, 489 

 specificity of, 487 



studies of Rosenau and Anderson, 

 471 



symptoms in dogs, 470 

 Theobald Smitli phenomenon, 471 

 theories of, 492-493 

 tissues involved, 490 

 turtles and, 483, 484 

 washed precipitates and, 488 

 Anatomical factors, 70 

 Anatoxin, history of, 247 

 Anergy, 434 

 Anilin dyes, history of use, 87 



use of, in hematology, 87, 88 

 Animal parasites, immunity mech- 

 anisms against, 135 

 tissue resistance to Cysticercus 

 pisiformis, 135 

 proteins, nature of, 321, 322 

 reagins, 150, 151 

 Animals, agglutinogens in, 174 

 bleeding of, 227 

 effect of toxin on, 242, 243 

 inoculation • of, according to Dean, 

 226 

 to Kolmer, 226 

 lipoid differences in antibodies of, 

 196 



