618 



SUBJECT INDEX 



Conipleinent fixation — Cont 'd 



bacterial antigens used in, -iO'j 



basis of bacterial, 401-418 



by-products of lysis and, 164 



development of modern tech- 

 nique, 4on 



diluents used in, 405 



discussion of bacterial, 418-415 



Eagle's studies, 165 



effect of kind of lipoid in, 196 



final volume in, 416 



glassware in, 416 



gonococcal infection and, 413 



history of, 401 



inactivation of sera for, 417 



Kolmer's recommendations, 415- 

 417 



mechanisms of, 165, 435 



methods available, 409 



modifications of original, 404, 

 405 



necessary controls in, 409-412 



nonspecific reactions in, 149, 4.".4 



original technique, 401. 402 



precipitates and, l(il 



protocol of Bordet, 402 



of simplified bacterial, 410 



quantitative and qualitative 

 tests, 413 



reagents and factors involved, 

 403 



reporting results, 413 



results due to antibodies, 412 



specific, 161 



syphilis and, 419 



time and temperature of incuba- 

 tion, 416 



tuberculosis and, 413 

 fourth component of, 157 

 Kolmer's full unit of, 204, 416 



method of titrating, 203, 204 

 nature of, 157, 158 



of end-piece and fourth com- 

 ponent, 158 

 nonspecific adsorption of, 162 

 opsonification and, 96 

 origin of, 160 



phospliatide fraction of, 158 

 preservation of, 158, 159, 416 

 reversibility of reaction, 159 

 role of, 145 

 specific fixation of, 161 

 time of fixation, 161, 162 

 unit of, 203, 204 

 various animals and, 160 

 Concentration of antihodv, historv 

 of, 285 



Conglutinins, discovery of, 152 

 Conjugated antigens, 335 

 Landsteiner 's, 378 

 studies of Averv and Goebel, 360, 

 361 

 proteins, antigenicity of, 322 

 Conjunctival tests, 571 

 Constancy of characters, theory of, 



41, 42 

 Contact dermatitis, causes of, 568, 



569 

 Contagious disease, definition of, 32 

 Contralateral injection, skin allergy 



and, 561 

 Controls, complement fixation and, 



412 

 Convalescent and immune sera, 27()- 

 305 

 serum, blanching test and, 279 

 danger of intraspinal, in polio- 

 myelitis, 292 

 measles and, 290 

 mumps and, 292 

 poliomyelitis and, 292 

 scarlet fever and, 279, 280 

 variola and, 292 

 virus disease and, 289 

 Corynebacterium diphtheriae, aviru- 

 lent toxicogenic strains of, 

 244 

 hypersensitivity to toxins of, 41 

 identification of, 393, 394 

 invasive powers of, 152, 242 

 toxin of, 245 

 Coughing reflex, value of, 71 

 Cow's milk, precipitins for, 222 

 Criteria of anaphylaxis, 485, 486 

 Critical potentials, agglutination and, 



213 

 Cross reactions, pneumococcus Type 

 II and Friedlander 's ba- 

 cillus, 154 

 Tvpe XIV and liuman EEC, 

 358 

 rickettsia and proteus 0X19, 154 

 tularemia and brucellosis, 390 

 Croton tiglium toxin, 35 

 Cryo-ehem process, preservation of 



complement by, 158 

 Crystalline lens, non-species specific- 

 ity of protein of, 322, 325 

 Crystalloids, 584 

 Customs, effect of, in freedom from 



disease, 50 

 Cysteine, diazotization of, 338 

 Cysticercus pisiformis, tissue resist- 

 ance to, 135 

 Cystitis, factors in, 81 



