SUBJECT INDEX 



635 



'I'etaiius — Coiit M 



antitoxin, reasous i'ur iut'tfectivo- 

 ucss of, 29;> 

 unit of, 200, 201 

 cause of, o3 



discovery of etioloyic agent of, 242 

 etiology of, 2!l.'I 

 propiiylaxis, IK!, US, 2!):; 

 theories of nie<'lianisnis in, 293 

 therapy ami antitoxin, 2()4, 29.''> 

 toxin, discovery of, 242 

 pathwav to cord, 293 

 to CNS, 33 

 toxoid, immunization with, 11(5, 118 

 Theobald Smith phenomenon, 471 

 Theories of adsorption, 162 

 Theory, Arrheuius and Madsen 's, of 

 toxin-antitoxin, 252 

 as to filterable forms of bacteria, 



43 

 Bernstein's triple allelomorph, 178 

 Bordet's, of toxin-autitoxin, 252 



two phase, 209 

 Breinl and Haurowitz, of antibody 



formation, 198 

 Duclaux's, on mechanism of coagu- 

 lation, 209 

 Eaton's bacterial toxin formation, 



245 

 Ehrlich 's, of toxin-antitoxin, 252 

 Gruber's, of agglutination, 200 

 Heidelberger and Kendall 's, of 

 precipitin reaction, 212, 

 213 

 humoral, 143 



Manwaring's of anaphylaxis, 312 

 mechanisms of anaphylaxis and, 



492, 497 

 monophyletic, 91 

 Nageli "s, as to lack of constancy 



of characters, 41 

 Neufeld's regarding resistance, 107 

 of constancy of characters, 41 

 polyphyletic, 91 

 Sabin's, of antibodv formation, 



198 

 serum sickness and, 310, 311 

 unitarian, of antibodies, 198, 199 

 Therapeutic agents, antitoxins, 257 

 Therapy, underlying principles of, 84 

 Thermal reactions, 3>0(i 

 Tliiocvanates, etfect on precipitin test 



of, 233, 2.".4 

 Thyroglobulin, antigenicity of, 323 

 Tillett and Francis, C substance of. 



359 

 Timothv bacillus, chemistry of, 3i55 



Tissiic extiacls, tiocculalion tests and, 

 447 

 iuununily, 12S-I40 

 pi-oteins, specificity of, 322 



summary of Cannon's work, 130 

 Tissues, establishment of bacteria in, 



74 

 Titer, diagnostic tularemia, 383 

 tyi)hoid fever, 380 

 undulant fever, 383 

 Widal test, 380-382 

 variation in, 414 

 agglutinin, 414 

 hemolysin, 414 

 infection and, 415 

 Titration, hemolytic, anticomplement- 

 ary, antigenic, of bacteri- 

 al, 406-408 

 precipitin after Nuttall, 227 

 after Uhlenhuth, 227 

 Tolerance, in toxemic diseases, 139 

 Tonsillar ring, nature and importance 



of, 71 

 Tonsils, drainage of, 75 

 Toxemic diseases, examples of, 32, 33 



tetanus, 293 

 Toxin, and antitoxin, intracutaneous 

 titration of, 254, 255 

 discovery of bacterial, 242 

 doubt regarding meningococcus ex- 

 otoxin, 289 

 effect of diphtheria on animals, 

 242, 243 

 of physical and chemical agents 

 on, 24() 

 Ehrlich 's spectrum, 252 

 high potency production of, 246 

 measurement of, by Ehrlich, 247, 



248 

 M.R.D. and L, doses of, 254 

 Ramon 's method of titrating, 248 

 source and nature of diphtheria 



toxin, 245 

 standardization of, bv flocculation, 



249 

 tetanus, pathway to CNS, 3;; 

 unit of streptococcus scarlatinal, 

 279 

 Toxin-antitoxin, flocculation, source 

 of precipitate, 251 

 specificity of, for toxin, 251 

 reaction, Ehrlich 's theory of, 251, 



252 

 serum reactions and, 30S 

 Toxins, action of, in gaseous gan- 

 g?-ene, 295 



