202 



INDEX 



Biological polymer, what determines 



the size of a — ?, 127 

 Biological role of nucleic acids, 26, 



70-72 

 , participation of proteins in, 



26, 73 

 5-Bromouracil, incorporation into 



DNA, biological consequences, 



143-146 

 — , — of E. coli thymine auxo- 



troph, 152-154 

 Bunched and solitary nucleotides 



(pyrimidine), 123, 148, 166 

 , schematic representation of 



a fragment of a double strand of 



DNA, 90, 132 



Calf liver, composition of RNA's 

 (table), 17 



Calf thymus DNA, 12, 138 



— , apurinic acid from — , 34 



— , enzymic degradation, 19, 31, 

 33 



— , fractional dissociation from his- 

 tone and globin complexes, 45— 

 50 



— , method of isolation, 129 



— , 5-methylcytosine distribution in, 

 56, 151 



Cell constituents, spatial conditions 

 under which the cell manufac- 

 tures its constituents, 116 



Cell and machine, 174, 175 



Cellular specificity, chemical basis, 

 102-104, 112, 113 



— , directive influence of proteins 

 and nucleic acids in maintenance 

 of_, 104 



— and heredity, 1 1 1 



Chemical concept of a molecule and 

 molecular biology, 182 



Chicken erythrocyte DNA, 30-32 



5-Chlorouracil, incorporation into 

 DNA, 152, 154 



Citrate ions, use in isolation of nu- 

 cleic acids for inhibition of deoxy- 

 ribonucleases, 6 



Clusters of nucleotides in DNA, 19 



, analysis of sequence, longer 



all-thymine than all-cytosine units 

 in many DNA's, 149 



Code-script of biological high poly- 

 mers, 117-124 



Coding of information and order of 

 alignment of the nucleotide mon- 

 omers in a nucleic acid, 124 



— for phenylalanine, 169 



— units for amino acids, critical 

 remarks, 168-172 



Comparative biochemistry, 112 



Compositional regularities in nucleic 

 acids 13, 28, 30, 51-52, 54, 66, 

 72, 86-88, 93-96, 106, 120, 127, 

 128, 131, 155, 164, 170 



Conjugated proteins, 78-81 



Conjugation in the formation of 

 macromolecules, role in biochem- 

 ical evolution, 78 



Cybernetics, 113 



Cytidine, isolation and estimation, 9 



Cytochrome b2, polydeoxyribonu- 

 cleotide component of — , 128 



Cytoplasm of rat liver and kidney, 

 nucleotide ratios in ribonucleo- 

 proteins, 94, 119 



Cytosine, decomposition to uracil 

 by heating with strong acid, 10 



Cytostatic and cytotoxic chemicals 

 which are incorporated into nu- 

 cleic acids, 71 



Deoxy cytidine and thymidine 3',5'- 

 diphosphates released from DNA 

 of various organisms (table), 92, 

 136, 138, 141, 142 



Deoxymethylcytidine 3 ',5 '-diphos- 

 phate, 140 



Deoxypentose nucleic acid(s), see 

 also deoxyribose nucleic acid(s), 

 deoxyribonucleic acid(s), DNA 



— , sugar in—, 18, 53, 65, 84 



Deoxypentose nucleoprotein(s) of 

 calf thymus and wheat germ, 

 course of dissociation at rising 

 NaCl concentrations, 46, 65 



