SYMBOLS 



XV 



turnover number 

 rate of reaction 

 rate of forward reaction 

 final rate of reaction 

 rate of inhibited reaction 

 initial rate of reaction 

 rate of the n^"^ step in multi- 

 enzyme system 

 rate of reverse reaction 

 rate of resistant reaction 

 rate of sensitive reaction 

 steady-state rate of reaction 

 total rate of reaction 

 water 



electrostatic factor 

 transferred group 

 specific concentration of X 

 valence of ion 



number of electrons in outer 

 shell 



... interaction constants giving 

 the effects of the binding of 

 one substance on the binding 

 of another to the active site 

 molecular polarizability 

 constant characterizing the 

 change in the rate of break- 

 down of the ES complex 

 molar depression of the dielec- 

 tric constant 



electrical potential between a 

 particle and the medium 

 angle between dipoles 

 Debye-Hiickel constant 

 temperature characteristic 

 dipole moment 



mean (statistical) dipole mo- 

 ment 



frequency of electrical oscillator 

 heterogeneity index 

 specificity of inhibition 

 maximal specificity of inhi- 

 bition 



inhibition index (of Kistia- 

 kowsky and Shaw) 

 potential energy 

 equilibrium potential energy of 

 interacting particles 



