m.C^ 



Fig. 3-1. Several ways in which inhibitors can interfere with an enzyme reaction. 

 Molecules 1 and 2 are either two substrates or a substrate and coenzyme; X is a co- 

 factor, such as a metal ion, functioning in the binding of a substrate. The inhibitor 

 in every case is represented by the solidly shaded molecule. The positions assumed 

 by the reactants in the normal enzyme reaction are shown at the top. See the text 



for explanations. 



