EXPRESSION AND INTERPRETATION OF INHIBITION 



109 



will have /il/s outside this range. The heterogeneity index o must be 

 determined experimentally and in hapten-antibody reactions varied from 

 1.5 to 3 usually, with an average above 2, indicating a marked degree 

 of variation; there is no basis for estimating what the values of o 

 may be for enzymes. It is possible that the interpretation of K^ should 

 be made on a statistical basis and that interaction energies calculated from 

 them should be considered as average values. 



