REVERSIBLE MOXOLINEAR CHAINS 



339 



of reaction 2 is less than in the irreversible case. The steady-state level 

 of (B) will of course be different. The individual rates are: 



t'l = 



rx(A) 



(A) + K, 



K_,K, + Z_,(B) + ^,(0 



(7-18) 



(7-19) 



Fig. 7-11. Effect of the reverse reaction on the steady-state rate and intermediate 



concentration in a partially reversible monolinear chain. V ^ = 3, V^ = 1, X^ = 10 



mJ/, K^ = 1 mM, K^^ = 20 mJf, and (A) = 1 mM. 



from which the level of (B) is given by: 



K, F_,(C)i(A) + ZJ] + Fi(A)[(C) + K_,] 



(B) = 



^_. 



F,[(A) + K,] - F,(A) 



which reduces to Eq. 7-3 when the reverse reaction is zero. 



Finally, the system: 



E, E, 



(7-20) 



(7-2i; 



behaves similarly to system 7-13, (C) being kept constant, but (B) will be 

 different. The individual rates are given by Eqs. 7-14 and 7-19. The response 



