INDUCED REACTIVATION OF INHIBITED ENZYMES 



633 



Table 13-1 



Relative Potencies of Reactivators of Human Erythrocyte 



Cholinesterase Inhibited by Tetraethylpyrophosphate " 



" From Hobbigcr el al. (1958). 



^ The structures of the reactivators are inchided in text. 



rapid, reactivation is difficult. Spontaneous reactivation may proceed along 

 with the reactivation brought about by nucleophilic agents. The expres- 

 sions for the inhibition are easily obtained for these situations. Spontaneous 

 reactivation: 



EX 



E + X' 



ine 



-kt 



induced reactivation: 



EX 



R ^ E n- XR 



_- i g-fc'(R)( 



(13-49) 

 (13-50) 



(13-51) 

 (13-52) 



