920 



SUBJECT INDEX 



Addition reactions, kinetics of, 39-43 



Adenosinetriphosphatase (ATPase), 

 binding energy of terminal ATP phos- 

 phate to, 295 



effect of dielectric sonstant on, 294. 

 810-812 



of pressure on. 845-846 

 energy of binding of ATP to, 294-295 

 entropy in formation of ES complex, 

 266-267 



of ATP binding. 294 

 evidence for a water site, 44 

 inhibition by dinitrophenol, 



temperature characteristics of, 797 

 stimulation by phenylmercuric com- 

 pounds, 452 



Adenosinetriphosphate (ATP), depen- 

 dence of cellular function on. 464-466 



Administration, see Route of adminis- 

 tration 



Agonists. 



concentration of, 



effects of two inhibitors on, 506 

 inhibition of enzymes forming, 466-467 



of enzymes inactivating, 467-470 



Alcohol dehydrogenase, 

 complexes with DPN, 19 

 inhibition by jj-chloromercuribenzoate. 



reversal with GSH, 622 

 inhibition by o-phenanthroline, 84 



inactivation of enzyme during, 567 

 nature of H transfer in, 30 



of K,„. 21 



Aldolase, ES complex. 19 



Aldoximes, 



reactivation of inhibited cholinester- 

 ases, 630-633 

 kinetics of, 648 



Aliesterase, inhibition by insecticides, 

 473-474 



Amine oxidases, see also Monoamine oxi- 

 dase 

 inhibition by diamidines, 309-310 



Amines, tissue concentrations of, 



effects of multiple inhibition on, 506 



D-Amino acid oxidase, inhibition by chlor- 

 tetracycline, 90 



L-Amino acid oxidase, substrate inhi- 

 bition. 111. 133 



Amino acids, bond angles in, 240 



Aminoacylase I, substrate inhibition, 

 112, 130 



/j-Aminobenzoate, 



inhibition of D-amino acid oxidase, 90 

 of bioluminescence, effect of pressure 

 on, 851-852 



Amino group, 



binding energy to sarcosine oxidase, 



297 



configuration of, 235 



dipole angle of, 222 



dipole moment of, 222 



hydration of, 251, 255 



interaction with carboxylate group, 



270-273 



molar refraction of, 222 



polarization of benzene ring by, 298 



van der Waals radius of, 234 



m-Aminophenol, inhibition of D-amino 

 acid oxidase, 90 



3-Amino-l,2.4-triazole. inhibition of cata- 

 lase. 

 effect of temperature on. 755-756 



Ammonia, 



dipole moment of, 244 

 dispersion electrons of, 225 

 interaction energy contributions of, 244 

 molar refraction of, 225 

 optical constants, of, 225 

 polarizability of, 225 



a-Amylase, activation by Cl~, 834 



Amytal, on electron transport. 346 



Anions, inhibition of enzymes. 839-840 



Aniline, inhibition of D-amino acid oxi- 

 dase, 90 



Anoxia. 



differential damage to central nervous 

 system, 457 



to embryos, 457-458 



