SUBJECT INDEX 



923 



Buffer value, definition of. 709 



Bulk dielectric constant, definition of, 801 



Butyrylcholine, inhibition of choline- 

 sterase, 493-494 



Calcium, 



activation of cholinesterase, 837 

 binding to seralbumin, 818 

 distribution in the cell, 431 

 effect on substrate inhibition of chol- 

 inesterase, 127-128 



Carbamates, inhibition of biolumine- 

 scence, 



effect of pressure on, 851-852 

 of temjierature on, 790 



Carbon dioxide, 



dispersion electrons of, 225 

 energy constants of, 237 

 energy curve for interaction of, 236 

 interaction energy of, 237 

 molar refraction of, 225 

 optical constants of, 225 

 polarizability of, 225 



'Jarbon monoxide, 



dipole moment of, 244 

 dispersion electrons of, 225 

 inhibition of cytochrome oxidase, 9-10 

 interaction energy contributions of, 244 

 molar refraction of, 225 

 optical constants of, 225 

 polarizability of, 225 



Carboxylase, see Pyruvate decarboxylase 



Carboxylate group, 



binding to sarcosine oxidase, 295, 297 



bond angle in, 240 



configuration of, 235 



dispersion energy in hapten-antibody 



reactions, 278 



hydration of, 251, 255 



interaction with amino group, 270-273 



molar refraction of, 222 



polarization of benzene ring by, 298 



rate of proton association, 656 



van der Waals radius of, 234 



Carboxypeptidase , 

 active center of, 201 

 bindig energies of inhibitors of, 292-294 

 effect of dielectric constant on, 813-814 



of ionic strength on, 830 

 inhibition by dipeptides, effect of ionic 

 strength on, 837 



by phosphate, 839 

 nature of K,„, 21 

 substrate inhibition, 111, 120 



Catalase, 



adsorption at interphases, 436 

 complex with acetate, 840 

 enzyme-substrate complex, 19 

 heme in protein crevice, 198 

 inhibitions of, effect of temperature on, 

 755-756 



Cavity radii, for ions, 240-241 



Cellular function, 



changes in, relation to enzyme inhibi- 

 tion, 462-474 



dependence on ATP, 464-467 

 effect on inhibitions, 484-485 



on penetration of inhibitors, 484 

 level of, 



effect on inhibitions, 480-481 



in tissue slices, 480-481 

 metabolic basis studied with inhibi- 

 tors, 6 



methods of establishing correlations, 

 471-474 



nonenzymic effects of inhibitors, 463- 

 464 

 quantitative relations in, 471 



Cellular inhibition, 472-486 



effects of pH on, 713-718 

 of temperature on, 782-792 



rates of, 571-590 



reversal of, 642-646 

 Cellular variations, in tissue slices, 481 

 Chloral hydrate, inhibition of biolumi- 



nescence, 



effect of pressure on, 851-852 



Chlorella, 



glucose effect on respiration and ATP 

 level, time relations of, 389 



