924 



SUBJECT INDEX 



photosynthesis in, inhibition by iodo- 

 acetamide, 519-520 



Chlorguanide (Paludrine), concentration 

 in tissues, 395, 399 



Chloride, 



binding to seralbumin, effect of tem- 

 perature on, 753 

 concentration in tissues, 430 



Chlormerodrin (Xeohydrin), 



correlation of inhibition with renal con- 

 centration, 405 

 kidney-plamsa ratio of, 396-397 



Chloroform, inhibition of biolumines- 

 cence, 

 effect of pressure on, 851-852 



p-Chloromercuribenzoate, 



displacement of re++ from homogen- 



tisate oxidase, 625 



effect on muscle contractility, 462-463 



inhibition of lactate dehydrogenase, 



rate of, 546, 549 



of i^yruvate decarboxylase, protec- 

 tion by substrate, 558 

 of succinate dehydrogenase, rate of, 

 547, 549 



reversal of inhibitions due to, 622 



Chlortetracycline, inibition of D-amino 

 acid oxidase, 90 



Choline, inhibition of cholinesterase, 

 effect of temperature, on, 760 



Cholinesterase, 



active center of, 200 



boundary conditions for noncompeti- 

 tive inhibition of. 71 



carbamylation of, 634-636 



determination of serum concentration 



of, 71-72 



different types in serum, 485-486 



dispersion interaction, 

 of benzene ring, 290 

 of halogen groups, 288-290 

 of trimethylammonium ion, 245 



effect of ionic strength on, 827-828 

 of substituent position on inhibitors, 

 290-291 



of temperature on inhibition of, 758 - 

 760 

 inhibition at junctions, 467-470 

 by alkylammonium ions, 285-288 

 by p-chloromercuribenzoate, failure 

 of cysteine to reverse, 622 

 by E-600, 590-591 

 by HgCla, 545-547 

 by insecticides, 473-474 

 by organophosphorus compounds, 

 induced reactivation, 630-636 

 kinetics of reversal, 646-648 

 reactivation during, 569 

 spontaneous reactivation, 627-630 

 by phenothiazines, effect of Ca++ on, 

 837 



by phenyltrimethylammonium ions, 

 290-291 

 by physostigraine, 



dilution effect on, 611 

 effect of ionic strength on, 836 

 rate of, 554, 557-558 

 reversal by destruction of inhi- 

 bitor, 640-641 



reversal rate after adding sub- 

 strate, 613-615 

 by quinine, temperature characteris- 

 tics of, 795-796 

 interaction of substrates and inhibi- 

 tors with, 284-292 

 ion-ion interactions of, 284-288 

 multiple inhibition of, 493-495 

 product inhibition of, 146 

 role of water in kinetics, 45 

 substrate inhibition, 111, 121-122, 125- 

 128, 138-139 



effect of ionic strength on, 838 

 synthesis of new enzyme following 

 irreversible inhibition, 645 



a-Chymotrypsin. 



association of imits of, 655 



effect of dielectric constant on, 809-811 



of ionic strength on, 828-829 

 entropy change in formation of ES 

 complex, 266 



enzyme-substrate complex, 19 

 formation from chymotrypsinogen, 197 



