926 



SUBJECT INDEX 



Copper, 



binding to imidazole, 314 



to seralbumin, 266, 314-315 

 effect of temperature on, 753 

 complexes with ammonia, 313 

 hydration of C'u++, 251 

 inhibition of respiration, rate of, 581- 

 582, 588-590 



lethal action on Nitella, concentra- 

 tion-time curves of, 598 



Coupling inhibition (uncompetitive in- 

 hibition), 



by substrate, 118-119 

 definition and equations of, 59-60 

 types of plots obtained, 160, 166 

 Covalent bonds, nature of, 205-206 

 Covalent bond lengths, table of, 238 

 Covalent radii, of atoms, 233 

 Critical temperatures, 

 definition of 794-795 

 in inhibition of cholinesterase by qui- 

 nine, 796 



possible reasons for, 795 

 Crossover points, definition of, 518 



Crotonase, inhibition by jo-chloromercuri- 

 benzoate, 



failure of cysteine and GSH to reverse, 

 622 



Cumulation, see Accumulation 

 Cyanide, 



diversion of electron flow, 454 

 effect on adenine nucleotides and phos- 

 phates in yeast, time relations of, 389 



on spectra of yeast cytochromes, 517 

 inhibition of cytochrome oxidase, 9 



of respiration, effect of temperature 



on 782-784 



of sea urchin respiration, 8 



of succinate oxidase, effect on tem- 

 perature characteristics, 798 

 resistant fraction of metabolism, 447- 

 448 



stimulation by removal of inhibitory 

 metal ions, 453 



treatmant of poisoning by forming 

 methemoglobin, 615 



Cyclic systems, 348-354 



effect of cycle intermediates on, 35' 

 of substrate concentration on, 350- 

 351 

 of temperature on, 772 



multiple inhibition of, 501 

 Cyclohexane ring, dispersion energy in 



reaction with carboxypeptidase, 294 

 Cysteine, 



ionization microconstants for, 703 



reversal of inhibitions by mercurials, 



622 

 Cytochrome c reductase, active center 



of, 200 

 Cytochrome oxidase, 



effect of ionic strength on, 832 



inhibition by bicarbonate, 832, 839 



Deacylases, function in divergent chains, 

 344 



Debye, definition of, 210 



Denaturation, effects on enzyme inhi- 

 bition, 760-768 



Deoxyribonuclease, effect of ionic strength 

 on, 8.30-831 



Destruction of inhibitor, effect on inhi- 

 bitions, 637-642 



DFP, see diisopropylfluorophosphate 



Diamidines, inhibition of amine oxid- 

 ases, 309-310 



Diamine oxidase, substrate inhibition, 



HI 

 Diamox, see acetazolamide 

 Diaphragm, rate of Hg-^^ uptake by, 590- 



591 

 Diatoms, respiration of, 



stimulation by arsenite, 452 

 2,4-Dichlorophenol, inhibition of catal- 



ase, 



effect of temperature on, 755-756 

 Dielectric constant, 



definition of, 245 



effect of ionic strength on. 815-816 



